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Homologous Recombination Repair Gene Mutations to Predict Olaparib Plus Bevacizumab Efficacy in the First-Line Ovarian Cancer PAOLA-1/ENGOT-ov25 Trial January 2023 JCO Precision Oncology 7(7):e2200258 PURPOSE The PAOLA-1/ENGOT-ov25 trial of maintenance olaparib plus bevacizumab for newly diagnosed advanced high-grade ovarian cancer demonstrated a significant progression-free survival (PFS) benefit over placebo plus bevacizumab, particularly in patients with homologous recombination deficiency (HRD)–positive tumors. In case you are seeking for sites, which predict soccer matches accurately, then king Victor. 5. Their exclusive interface makes it easier to locate the markets where they are quite interested in. com says that they provides free football tips, sure soccer predictions and football predictions for more than 860 football leagues and can be used to bet on platforms like Bet9ja, Surebet, Nairabet and others. Wednesday Predictions. 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